First prospective analysis links breast and pancreatic cancer risk with lynch syndrome
A new prospective study of patients with Lynch syndrome an inherited disorder of cancer susceptibility caused by mutations in specific DNA repair genes provides the first strong evidence that people with Lynch syndrome face significantly increased risks of breast and pancreatic cancers. The study also provided new, clearer estimates of the risks of cancers already recognized to be associated with Lynch syndrome, including those of the colon, uterus, ovary, kidney, stomach and bladder. The findings published February 13 in the Journal of Clinical Oncology may have implications for screening and early detection of cancers in patients with the condition. Additionally, the study showed that relatives of individuals with Lynch syndrome who do not carry a genetic mutation associated with the condition have no increased risk of developing cancer, compared to the general population....
Source: PhysOrg - Monday, 13 February
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